Marion G. Peters, M.D.
- Professor, Department of Medicine
- John V. Carbone, M.D., Endowed Chair in Medicine
- Chief of Hepatology Research
Contact Information
Education
Melbourne University Medical School, Melbourne, Australia, M.B.B.S., 1972, Medicine
St. Vincent's Hospital Medical School, Melbourne, Australia, Medicine
Melbourne University, M.D., 1991, Medicine/Immunology
Residencies
- 1973-76 Resident and Registrar in Internal Medicine, St.Vincent's Hospital, Melbourne, Australia
- 1976-77 Clinical Research Registrar to Dr. I. R. Mackay, Royal Melbourne Hospital and The Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia
Fellowships
- 1977-78 Gastroenterology Registrar, St. Vincent's Hospital, Melbourne, Australia
- 1978-80 Clinical Research Fellow in Hepatology to Dr. T. B. Reynolds, University of Southern California, Los Angeles, CA
- 1980-83 Visiting Fogarty Fellow to Dr. A.S. Fauci, Laboratory of Immunoregulation, National Institute of Allergy and Infectious Disease, NIH, Bethesda, MD
- 1983-85 Visiting Staff Fellow to Liver Diseases Section, National Institute of Arthritis, Diabetes and Digestive and Kidney Diseases, NIH, Bethesda, MD
Clinical Expertise
- Alcoholic Liver Disease
- Autoimmune Hepatitis
- Benign Liver Tumors
- Cirrhosis
- Fulminant Hepatic Failure
- Hepatitis B
- Hepatitis C
- Hepatocellular Carcinoma (Liver Cancer)
- Live Donor Liver Transplantation
- Liver Transplantation
- Nonalcoholic Fatty Liver Disease
- Primary Biliary Cirrhosis
- Primary Sclerosing Cholangitis
Biography
Dr. Marion Peters is a Professor of Medicine and holds the John V. Carbone, M.D., Endowed Chair in Medicine. She is also Chief of Hepatology Research. Dr. Peters is especially interested in the immunology of chronic liver diseases, particularly viral and autoimmune hepatitis. Her research activities include studies of transgenic mouse models of liver specific T cell responses, HIV and HCV coinfection, and alcohol and HCV infection.
Dr. Peters graduated from Melbourne University Medical School, Australia in 1972. She trained in gastroenterology, hepatology and immunology at St. Vincent's Hospital, Melbourne, University of Southern California and National Institutes of Health. She was Chief of Hepatology and medical director of Liver Transplantation at Washington University School of Medicine from 1985 to 1998.
Research Overview
My major interest is in viral hepatitis and the role of the host immune response. My work focuses on interactions among alcohol use, cannabis use and HIV co-infection on fibrotic outcomes of HCV infection. We are currently evaluating the predictors of progression of liver disease in HIV and HCV coinfected women within the Women's Interagency HIV Study (WIHS): the role of alcohol, cannabis, HIV status and control as well as reproductive aging on the severity and rate of progression of liver disease.
We are also studying adherence to antiretroviral therapy in HIV/HCV co-infected women and on HCV-specific and innate immune responses in persons co-infected with HCV and HIV. I work within the AIDS Clinical Trial Group to develop clinical trials in viral hepatitis and HIV and within the Women's Interagency HIV Study (WIHS) to examine predictors of liver-related morbidity and mortality in a cohort of women with HIV/HCV infection.
Research & Funding
- UCSF Liver CenterSponsor: NIH/NIDDKSponsor ID: P30DK026743Funding Period:Jul 1985-May 2023Co-Investigator
- NRSA Hepatology Training GrantSponsor: NIH/NIDDKSponsor ID: T32DK060414Funding Period:Dec 2001-Jun 2022Co-Principal Investigator
- HIV status and reproductive aging affect liver fibrosis in HIV/HCV infected womenSponsor: NIH/NIAIDSponsor ID: R21AI088351Funding Period:Mar 2010-Feb 2013Principal Investigator
- General Clinical Research CenterSponsor: NIH/NCRRSponsor ID: M01RR000079Funding Period:Dec 1974-Mar 2009Co-Investigator
- HCV &ALCHOOL-- EPIDEMIOLOGY &HOST-VIRUS CORRELATESSponsor: NIH/NIAAASponsor ID: R01AA012879Funding Period:Sep 2000-Jul 2006Principal Investigator
- INTESTINAL IMMUNE RESPONSE INFLAMMATORY BOWL DISEASESponsor: NIH/NIDDKSponsor ID: R01DK050976Funding Period:Sep 1995-Aug 2001Principal Investigator
- INTESTINAL IMMUNE RESPONSE IN INFLAMMATORY BOWEL DISEASESponsor: NIH/NIDDKSponsor ID: R01DK043020Funding Period:Jun 1991-Oct 1995Principal Investigator
Clinical Trials
- Study ID: NCT00991289Start Date: Jan 2010Estimated Completion Date: Jan 2012Condition(s): HIV/AIDS, Hepatitis C
- Study ID: NCT00033163Start Date: Apr 2002Estimated Completion Date: May 2005Condition(s): HIV/AIDS, Hepatitis B
Publications
MOST RECENT PUBLICATIONS FROM A TOTAL OF 194
- Peters MG, Yuen MF, Terrault N, Fry J, Lampertico P, Gane E, Hwang C, Stamm LM, Leus M, Maini MK, Mendez P, Lonjon-Domanec I, Berg T, Wang S, Mishra P, Donaldson E, Buchholz S, Miller V, Lenz O. Chronic Hepatitis B Finite Treatment: similar and different concerns with new drug classes. Clin Infect Dis. 2023 Aug 26. View in PubMed
- Kang M, Price JC, Peters MG, Lewin SR, Sulkowski M. Design and analysis considerations for early phase clinical trials in hepatitis B (HBV) cure research: the ACTG A5394 study in persons with both HIV and HBV. J Virus Erad. 2023 Sep; 9(3):100344. View in PubMed
- Bhattacharya D, Tierney C, Butler K, Kiweewa FM, Moodley D, Govender V, Vhembo T, Mohtashemi N, Ship H, Dula D, George K, Chaktoura N, Fowler MG, Peters MG, Currier JS. Comparison of Antiretroviral Therapies in Pregnant Women Living With Human Immunodeficiency Virus and Hepatitis B Virus: A Randomized Controlled Trial. Obstet Gynecol. 2023 09 01; 142(3):613-624. View in PubMed
- Davwar PM, Okeke E, Duguru M, Nyam D, Bell K, Odeghe EA, Oyeleke G, Lesi OA, Singh R, Kim KY, Imade G, Akanmu AS, Sagay AS, Ogunsola FT, Peters MG, Roberts LR, Hou L, Murphy RL, Hawkins CA. Hepatocellular carcinoma presentation and prognosis among Nigerian adults with and without HIV. PLoS One. 2023; 18(3):e0282539. View in PubMed
- Wyles DL, Kang M, Matining RM, Murphy RL, Peters MG. Adverse Impact of HIV-1 on Long-term Outcomes Following HCV DAA Treatment: Final Results of ACTG A5320, the Viral Hepatitis C Infection Long-term Cohort Study (VHICS). Open Forum Infect Dis. 2023 Mar; 10(3):ofad115. View in PubMed
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