Norah A. Terrault, M.D., M.P.H.
- Professor of Clinical Medicine & Surgery
- Departments of Medicine & Surgery
- Director of Viral Hepatitis Research in Liver Transplantation
Contact Information
Division of Gastroenterology
513 Parnassus Avenue, Room S-357
San Francisco, CA 94143-0358
Phone: (415) 476-2227
415-476-0659
norah.terrault@ucsf.edu
Education
1985 B.MSc., University of Alberta
1987 M.D., University of Alberta
1997 M.P.H. University of California, Berkeley
Residencies
- 1987-88 Internship, University of Toronto
- 1988-91 Internal Medicine, University of Toronto
- 1991-93 Gastroenterology, University of Toronto
Fellowships
1994-95 Clinical Hepatology, Division of Gastroenterology, University of Toronto
1995-97 Research Hepatology, Division of Gastroenterology, UCSF Medical Center
Clinical Expertise
- Alcoholic Liver Disease
- Autoimmune Hepatitis
- Benign Liver Tumors
- Cirrhosis
- Fulminant Hepatic Failure
- Hepatitis B
- Hepatitis C
- Hepatocellular Carcinoma (Liver Cancer)
- Live Donor Liver Transplantation
- Liver Transplantation
- Nonalcoholic Fatty Liver Disease
- Pancreas Transplantation
- Primary Biliary Cirrhosis
- Primary Sclerosing Cholangitis
Biography
Dr. Norah Terrault is a hepatologist or liver specialist who is recognized internationally for the treatment of viral hepatitis and liver transplantation. Her research includes the study of viral hepatitis and its progression and treatment, especially in liver transplant patients. Her research includes several clinical trials related to preventing and treating chronic hepatitis C and B. Her studies in this area have been presented to the American Association for the Study of Liver Diseases, the leading organization for research in liver disease.
Terrault completed medical training at the University of Alberta and specialty medical training in Internal Medicine and Gastroenterology at the University of Toronto, both in Canada. Her post-doctoral fellowship in hepatology and viral hepatitis was completed at the University of California, San Francisco while earning a concurrent master's degree in public health from the University of California at Berkeley. She joined the medical staff at UCSF Medical Center in 1997.
Research Overview
My research focuses on the natural history and treatment of hepatitis C virus (HCV) and hepatitis B virus (HBV), particularly in special populations, including those undergoing liver transplantation. Work in progress addresses the natural history of post-transplant disease and specific therapies to prevent infection or modify HCV and HBV disease progression and loss of grafts from recurrent disease.
Our virological analyses are focused on characterization of viral mutations that occur in liver transplant recipients receiving antiviral therapies and assessment of the effect of these variant viruses on the natural history and severity of disease post-transplantation. Knowledge of these factors may allow improved organ allocation by identifying subsets of patients with HCV recurrence in liver grafts who would be favorable or unfavorable candidates for retransplantation.
Research & Funding
- USC Cirrhosis Clinical CenterSponsor: NIHSponsor ID: U01DK130197Funding Period:Sep 2021-Aug 2026Principal Investigator
- Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN)Sponsor: NIH/NIDDKSponsor ID: U01DK061738Funding Period:Jun 2002-Jun 2024Principal Investigator
- Hepatitis B Research Network (HBRN): Natural History and Treatment StudiesSponsor: NIH/NIDDKSponsor ID: U01DK082944Funding Period:Sep 2008-May 2020Principal Investigator
- Bay Area Hepatitis C Cooperative Research CenterSponsor: NIHSponsor ID: U19AI088790Funding Period:Jun 2010-May 2015Co-Investigator
- General Clinical Research CenterSponsor: NIH/NCRRSponsor ID: M01RR000079Funding Period:Dec 1974-Mar 2009Co-Investigator
- Resistance to Antiviral Therapy in Chronic Hepatitis CSponsor: NIH/NIDDKSponsor ID: U01DK060346Funding Period:Aug 2001-Apr 2007Principal Investigator
Clinical Trials
- Study ID: NCT04801849Start Date: Aug 2021Estimated Completion Date: Feb 2024Condition(s): Liver Disease, Nonalcoholic Fatty Liver Disease, Nonalcoholic Steatohepatitis, Steatohepatitis
- Study ID: NCT04454463Start Date: Aug 2020Estimated Completion Date: Jun 2024Condition(s): Liver Disease
- Study ID: NCT03619837Start Date: Jul 2018Estimated Completion Date: Jan 2021Condition(s): Hepatitis C, Transplantation Disease Transmission, Kidney Transplant
- Study ID: NCT01804829Start Date: Jun 2013Estimated Completion Date: Jun 2016Condition(s): Hepatitis C, Viruses, Hepatocellular Carcinoma, Liver Cancer, Hepatitis, Cirrhosis, Liver Transplant
- Study ID: NCT01474811Start Date: Nov 2011Estimated Completion Date: Dec 2020Condition(s): Hepatitis C
- Study ID: NCT01030484Start Date: Dec 2009Estimated Completion Date: Mar 2021Condition(s): Liver Disease
- Study ID: NCT01421212Start Date: Nov 1999Estimated Completion Date: Feb 2002Condition(s): Hepatitis B, Liver Disease, Liver Transplant
Publications
MOST RECENT PUBLICATIONS FROM A TOTAL OF 367
- Terrault NA, Slepin J, Kanner R, Gailloux K, Catalli L, McKinney J, Straley S, Morris P, Hluhanich R, Gonzalez-Flores A, Dodge J, Sarkar S. Strategies to Increase Primary Care Provider Capacity for Hepatitis C Care: The California ECHO-PLUS Study. J Viral Hepat. 2023 Jan 25. View in PubMed
- Hsu CC, Dodge JL, Weinberg E, Im G, Ko J, Davis W, Rutledge S, Dukewich M, Shoreibah M, Aryan M, Vosooghi A, Lucey M, Rice J, Terrault NA, Lee BP. Multi-Centered study of patient outcomes after declined for early liver transplantation in severe Alcohol-associated hepatitis. Hepatology. 2023 Jan 19. View in PubMed
- Feld JJ, Wahed AS, Fried M, Ghany MG, Di Bisceglie AM, Perrillo RP, Khalili M, Yang X, Belle SH, Janssen H, Terrault N, Lok AS, Hepatitis B Research Network (HBRN). Withdrawal of long-term nucleotide analogue therapy in chronic hepatitis B: Outcomes from the withdrawal phase of the HBRN immune active treatment trial. Am J Gastroenterol. 2023 Jan 13. View in PubMed
- Lim SG, Baumert TF, Boni C, Gane E, Levrero M, Lok AS, Maini MK, Terrault NA, Zoulim F. The scientific basis of combination therapy for chronic hepatitis B functional cure. Nat Rev Gastroenterol Hepatol. 2023 Jan 11. View in PubMed
- Kardashian A, Dodge JL, Terrault NA. Quantifying the Negative Impact of Fast-food Consumption on Liver Steatosis Among United States Adults with Diabetes and Obesity. Clin Gastroenterol Hepatol. 2023 Jan 10. View in PubMed
- View All Publications
In the News
- UCSF Transplant Surgery - December 20, 2014A new video on AASLD TV (American Association for the Study of Liver Diseases) features the UCSF Liver Transplant Program and faculty John P. Roberts, M.D., Norah A. Terrault, M.D., M.P.H. and Francis Y.K. Yao, M.D. As a leader in the treatment of liver disease and transplantation, UCSF has performed more than 2,500 liver transplants in both children and adults, many in their growing living donor liver transplantation program. The UCSF team is also researching cures for hepatitis as well as [...]
