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LiverSource »  Faculty »  Program Leadership »  Nancy L. Ascher, M.D., Ph.D.

Nancy L. Ascher, M.D., Ph.D.

Professor of Surgery
Division of Transplant Surgery
Isis Distinguished Professor in Transplantation


Contact Information

Academic Office
415-353-9321
nancy.ascher@ucsf.edu
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  • University of Michigan, Ann Arbor, MI, B.A., 1967-70
  • University of Michigan Medical School, Ann Arbor, MI, M.D., 1970-74
  • University of Minnesota, Minneapolis, MN, Ph.D., 1974-85
  • University of Minnesota, Department of Surgery, Minneapolis, MN,  Surgical Internship, 1974-75
  • University of Minnesota, Department of Surgery, Minneapolis, MN, Surgical Residency, 1975-77
  • University of Minnesota, Department of Surgery, Minneapolis, MN, Surgical Residency, 1979-81
  • University of Minnesota, Department of Surgery, Minneapolis, MN,   Transplant Fellowship, 1981-1982
  • University of Minnesota, Department of Surgery, Minneapolis, MN, Research Fellowship, 1977-79
  • American Board of Surgery, 1982, renewed 2012
  • End-Stage Kidney Disease
  • Fulminant Hepatic Failure
  • Hepatitis B
  • Hepatitis C
  • Hepatocellular Carcinoma (Liver Cancer)
  • Kidney Transplantation
  • Liver Cysts
  • Liver Transplantation
  • Living Donor Liver Transplantation
  • Living Donor Kidney Transplantation
  • Non-alcoholic Fatty Liver Disease
  • Pediatric Kidney Transplantation
  • Pediatric Liver Transplantation
  • Portal Hypertension
  • Clinical Transplantation
  • Recurrence After Liver Transplantation
  • Transplant Ethics
  • Transplant Policy

Dr. Nancy Ascher has devoted her career to organ transplants and transplant research. Dr. Ascher completed her undergraduate and medical education at the University of Michigan, Ann Arbor. She then went on to complete a general surgery residency and clinical transplantation fellowship at the University of Minnesota. 

Dr. Ascher joined the faculty of the Department of Surgery at the University of Minnesota in 1982 and was named Clinical Director of the Liver Transplant Program. She was recruited in 1988 by the UCSF Department of Surgery to build a liver transplantation program. In 1991, she was appointed Chief of Transplantation, an expanded role that included liver, kidney and pancreas transplants.

In 1993, Dr. Ascher was appointed Vice-Chair of the UCSF Department of Surgery, and in 1999 was appointed Department Chair where she served until September 2016.

Dr. Ascher has had a distinguished career of public service that includes appointments to the Presidential Task Force on Organ Transplantation and the Surgeon General's Task Force on Increasing Donor Organs. She also served as Chair of the Advisory Committee on Organ Transplantation for the Secretary of Health and Human Services from 2001 - 2005. Highly respected by her peers, Dr. Ascher was named to the list of U.S. News "America's Top Doctors," a distinction reserved for the top 1% of physicians in the nation for a given specialty.

Dr. Ascher is a Fellow of the American College of Surgeons and holds memberships in numerous other medical societies. She has taken an active leadership role in American Society of Transplant Surgeons activities and was its past-president. Dr. Ascher has published over 425 articles in medical and scientific journals. Her research interests are in hepatocyte immunogenicity, mechanisms of allograft rejection and clinical transplantation.

I. RECURRENT DISEASE AFTER LIVER TRANSPLANT
The NIH Liver Transplant Data Base has been extended to address the important issue of disease recurrence after liver transplantation. Although short term liver transplant results have improved markedly over the past ten years, it is apparent that disease recurrence is an important source of patient morbidity and graft loss. Long term following of greater than 1000 patients in the Liver Transplant Data Base will facilitate our understanding of the factors associated with graft recurrence.

II. EXPANDED CRITERIA FOR LIVER TRANSPLANT FOR HEPATOCELLULAR CARCINOMA
We have redefined the criteria for liver transplantation beyond the Milan criteria. The UCSF criteria enables additional patients to benefit from liver transplants without compromising outcome.

MOST RECENT PUBLICATIONS FROM A TOTAL OF 384
Publications provided by UCSF Profiles, powered by CTSI.
  1. Locke JE, Shelton BA, Olthoff KM, Pomfret EA, Forde KA, Sawinski D, Gray M, Ascher NL. Quantifying Sex-Based Disparities in Liver Allocation. JAMA Surg. 2020 May 20; e201129. View in PubMed
  2. Braun HJ, Dodge JL, Grab JD, Schwab ME, Liu IH, Glencer AC, Stock PG, Hirose R, Roberts JP, Ascher NL. Live Donor Liver Transplantation in the United States: Impact of Share 35 on Live Donor Utilization. Transplantation. 2020 May 18. View in PubMed
  3. Ahn C, Amer H, Anglicheau D, Ascher N, Baan C, Bat-Ireedui B, Berney T, Betjes MGH, Bichu S, Birn H, Brennan D, Bromberg J, Caillard S, Cannon R, Cantarovich M, Chan A, Chen Z, Chapman JR, Cole EH, Cross N, Durand F, Egawa H, Emond J, Farrero M, Friend F, Geissler EK, Ha J, Haberal M, Henderson M, Hesselink DA, Humar A, Jassem W, Jeong JC, Kaplan B, Kee T, Kim SJ, Kumar D, Legendre C, Man K, Moulin B, Muller E, Munkhbat R, Od-Erdene L, Perrin P, Rela M, Tanabe K, Tedesco Silva H, Tinckam KT, Tullius SG, Wong G. Global Transplantation COVID Report March 2020. Transplantation. 2020 Apr 01. View in PubMed
  4. Braun HJ, Ascher NL. Opioid Use and Liver Transplantation. Transplantation. 2020 Feb 04. View in PubMed
  5. Lebares CC, Guvva EV, Desai A, Herschberger A, Ascher NL, Harris HW, O'Sullivan P. Key factors for implementing mindfulness-based burnout interventions in surgery. Am J Surg. 2020 02; 219(2):328-334. View in PubMed
  6. View All Publications

 

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